The present study aimed to examine the effectiveness of a wisdom-based educational package on students’ self-compassion and happiness. A quasi-experimental method with a pretest–posttest control group design was employed. The statistical population consisted of students at Allameh Tabataba’i University, from whom a convenience sample was selected and randomly assigned to experimental and control groups. The experimental group participated in eight sessions of the wisdom-based educational package, whereas the control group received no intervention. Research instruments included the Self-Compassion Questionnaire and the Happiness Questionnaire, administered at pretest and posttest stages. Data were analyzed using descriptive statistics and multivariate and univariate analyses of covariance (MANCOVA and ANCOVA) with SPSS version 26. The findings indicated that, after controlling for pretest effects, there were significant differences between the experimental and control groups in self-compassion and happiness, such that posttest mean scores for both variables were significantly higher in the experimental group than in the control group. These results suggest that wisdom-based training—by enhancing self-awareness, emotion regulation, empathy, and realistic acceptance of difficult life experiences—can foster a kinder attitude toward oneself and promote greater happiness among students. Overall, the findings support the effectiveness of the wisdom-based educational package in enhancing self-compassion and happiness and underscore the importance of incorporating wisdom-based educational interventions into university educational and counseling programs to promote students’ psychological well-being.